The Op. 4 Serenade was composed around 1812. It was a time during which the serenade was an exceptionally popular format among the music public and home music makers. Kuffner's were among the very best. This Serenade was scored for Flute or Violin, Viola or Violin, and Piano or Guitar. It is in four charming movements - Allegro, Andante con moto, Minuetto, and Rondo scherzando, which interestingly juxtaposes Russian and Hungarian themes. The work was quite popular and went through several reprints and editions with the version for Flute, Violin, and Piano ultimately becoming the most popular.